Oral Presentation Society of Obstetric Medicine of Australia and New Zealand ASM 2015

CPAP (#47)

Sue Walker 1
  1. Mercy Hospital for Women, University of Melbourne, Melbourne, VIC, Australia

Sleep Disordered Breathing (SDB) is characterized by repeated episodes of upper airway obstruction, resulting in hypoxemia, hypercapnia and sleep fragmentation. Sequelae include sympathetic activation, increased oxidative stress and a generalized inflammatory response, which is responsible for the observed increase in long term hypertension and cardiovascular risk. Given many of the physiological pathways associated with SDB are common to pre-eclampsia, it is intriguing to consider the consequences of such events on hypertensive disorders of pregnancy. If SDB may be an important contributor to the development of pre-eclampsia, it would be particularly important, given that a safe and effective therapy is available in the form of Continuous Positive Airway Pressure (CPAP).  This talk will provide an overview of the current evidence linking sleep disordered breathing and pre-eclampsia and the potential therapeutic role of CPAP.